Best MSM For Cats: Buying Guide & Our Top Picks (Review 2020)

a white cat

As your cat ages, they are more susceptible to significant issues with pain, inflammation, joint problems, fatigue, coat issues, and general impairments of everyday functions. 

Pets must have adequate MSM in their body to function optimally. Unfortunately, most pets struggle to get access to adequate sulfur. This is largely due to modern farming and pet food production methods, which has decreased the amount of sulfur found naturally in food sources, leaving most animals in a significantly deficient state. 

Even if your cat is getting adequate sulfur, they can greatly benefit from the addition of MSM that can quickly help with joint and pain issues, and promote optimal overall health, wellness, and coat appearance.

Whether your cat is deficient in sulfur or is getting adequate sulfur in their diet, we’ve got it covered in our Buying Guide and our top 5 picks of Best MSM For Cats out there.

In a hurry? Click here to jump straight to the reviews!

What is MSM?

MSM (Methylsulfonylmethane) is a naturally occurring sulfur compound that’s used to improve immune function, reduce inflammation and help regenerate healthy body tissue. 

The reason MSM contains so many benefits is that it provides biologically active sulfur, which is the third most abundant mineral in the body and required to support multiple structure and function within the body, such as connective tissues and the respiratory system. 

MSM can be found is small quantities in fruits, vegetables, grains, milk, and meat. The compound itself is actually created naturally through the earth's sulfur cycle when phytoplankton and algae die and decompose. It then releases sulfur compounds into the atmosphere where they are transformed to DMS.

DMS is then converted to DMSO in the presence of ozone and sunlight. From there, they return to the earth's surface in rain water and is absorbed by plant life and ultimately eaten by animals. 

The commercially available MSM products are manufactured because the amounts found naturally are too small for extraction. MSM is produced when DMSO (dimethylsulfoxide) is oxidized. Then, it gets purified by either through crystallization or distillation method to remove impurities.

What does Sulfur do For Your Cat?

As cats get older, the concentration of sulfur in the body begins to decline. As a result, your cat may develop dull fur, skin problems, joint pain, brittle nails, poor gastrointestinal system, and generally weak immune system.

Other signs of sulfur deficiency:

  • Fatigue and lack of energy
  • Joint pain and inflammation
  • Shoulder and neck pain
  • Hip and leg pain

Although sulfur is present in all cells of the body, with the highest concentrations found in joints, hair, skin, and nails. However, the therapeutic benefits occur at levels much greater than what’s found in a regular diet.

One of the main reasons you want to get MSM supplement for your cat is because it works in conjunction with glutathione to help detoxify the body. When your cat's body is deficient of sulfur, the detoxifying process is hindered. As you can imagine, this leaves your furry friend susceptible to a lot of health problems.

Additionally, sulfur is actually not stored in the body but rather used and the excess amount is flushed out daily. For cats, especially senior cats, this can be a problem if they are not getting enough in their diet. 

Sulfur also plays in a different critical roles in the health of skin, bones, cartilage, and fur. More benefits include the following:

  • Promotes energy 
  • Enhances overall mobility
  • Reduces pain and inflammation
  • Potent detoxification for your cats's entire body
  • Maintenance of healthy skin and hair
  • Relief of some allergy symptoms
  • Helps remove parasites from the digestive tract
  • Promotes general wellness

Is MSM Safe For cats?

MSM is considered to be very safe. It has been used for decades for both humans and pets. However, at the beginning, your cat may experience some detoxification symptoms such as vomiting and diarrhea.

Don’t fret, these symptoms will disappear as your cat's body acclimatizes and stabilizes itself. It is advisable to administer MSM supplement to your cat with food to help decrease gastrointestinal upsets.

If your pet is on medications, make sure your vet knows about MSM so they can confirm the ability to integrate MSM into your cat's overall care and health management protocol.

Best MSM For Cats Comparison Chart

ImageProduct NameWeightRatingPrice
HappyBody Pure, Additive-free MSM

7 ounce (Crystals)check best price
Our Review
NODENS CAT Hip and Joint2 ounce (Liquid Formula)check best price
check best price
Our Review
Nature'sPure Edge MSM150 grams (Powder)check best price
Our Review
Lexelium Joint Support200 Grams (powder)check best pricecheck best price
Our Review
Kala Health MSMAvailable in 1, 10, or 33 pounds (Powder)check best pricecheck best price
Our Review

Buying guide: What to look out for when purchasing a MSM product

1. Price

The price of MSM supplements can vary greatly from one brand to another. If a product is overly priced, it doesn't absolutely mean it's a great product. It's also true if something is cheap it doesn't mean it's a low quality product.

Price alone doesn't guarantee the quality of a product. You also need to do your own research and compare products side by side to determine the best supplement for your cat.

2. Budget

Make sure to compare prices from different shops or online shops so that you get the lowest price for that particular supplement. You need to have your budget on check so that you only buy what you can afford. If you find that the product is either too expensive or too cheap, then look at the quality and other factors to find the best.

3. Flavor

It's also important to consider the flavor of a supplement, especially if your cat is a picky eater. It doesn't matter how great a product is if your the taste of the supplement is not appealing to your cat. Some MSM supplements are flavored with chicken or beef while other are not. Make sure you read the label carefully and choose the flavor your cat likes.

4. Different forms of MSM Supplement

Feline MSM supplements are available in liquid, powder, crystal, tablet and chew forms. Every cat has different preference, so learning what your cat likes and choosing supplements based on that knowledge can be very helpful.

Liquids - The liquid form is often more preferred as the ingredients are easily and quickly absorbed by your cat's body. It's also easier to mix the liquid with your cat's favorite food. 

Powders or crystals - Powers and crystals can easily be dissolved or mixed with your cat's favorite food.

Tablets - It can be a challenge to get your cat to swallow tablets. Additionally, the process of making tablets can have added binders and fillers which can significantly impact the amount of ingredients absorbed by your cat's body. If you buy  tablets, you can wrap the tablet with your cat's favorite food to hide it, making it easy for them to swallow. 

Chews - Chews are also easy to administer to your cat. Many companies have their chews flavored that your cat will like.

5. Know What You Are Looking For

Don't be enticed by advertisements that are very strategically done to promote their product. Make sure you know what you are looking for so you don't end up with a poor quality product that could potentially do more harm than good. 

Some companies may add words like "organic" "all natural" to entice you into buying it thinking that it is a great product for your cat. Make sure to  read ingredients and labels carefully. Additionally, do not hesitate to research well on the company that you will purchase supplements from.

6. Other Reviews

You may also want to check out how many other cat owners have purchased the supplement you are looking to buy. Inquiring your friends and relatives on the best products there are is another way to get reviews. 

Our Top 5 Picks Of Best MSM For Cats

1. HappyBody Pure, Additive-Free MSM

HappyBody MSM is a premium organic sulfur product to help relief chronic pain, inflammation, mobility issues, fatigue, and skin allergies in cats. You can rest assured that you are getting a quality MSM with HappyBody because it contains 99.9% pure MSM crystals free of additives or toxic fillers. 

Organic sulfur is crucial for a cat's body, joints, muscles, cells, skin, coat and much more. Without access to adequate sulfur, cat's body can breakdown faster over time. Even if your cat is getting enough sulfur, it can greatly benefit from the addition of pure MSM.

The crystals are very safe to use for pets. In fact, MSM is considered to be no more toxic than water. Common salt is actually more toxic than MSM.​

You will love that the crystal form provides an average of 5 to 10 times more MSM per dose than other forms, which is the best absorption and value for your money. Each bag contains 7 ounces which provides between 60 to 180 days supply depending on your cat's weight. 

If you have other pets such as horse or dog, this product can also be given to them as well. So you get one product that can benefit multiple pets. 

HappyBody uses the exact same premium organic sulfur that they use for people. The only difference is this product is further grind down the crystals to a finer crystal to make it easier to give to pets. 

This product is backed by a simple 100% satisfaction guarantee. If this product doesn't help your pet, you can return it for a full refund.

Many cat owners are extremely satisfied with the difference this product has made to their cat's energy level and mobility. If you want to see what others are saying about HappyBody MSM, click below to learn more:

Amazon's Customer Ratings: 4.2 Stars 


  • Can be used by cat, dog, and horse
  • 100% additive-free, pure, non-GMO MSM crystals
  • All batches 3rd party lab certified for purity and quality
  • 100% satisfaction guarantee
  • Made in an FDA registered lab
  • Tested for VOC's and heavy metals
  • Made directly from human-grade MSM
  • Fine crystals are easy to administer to pets


  • May be expensive for some cat owners
  • Bitter taste

2. Nodens Cat Hip and Joint

There is nothing is more painful than watching your once highly active cat slowing down and becoming less mobile due to joint problems. This makes it particularly important for pet owners to provide their cat with a high performance supplement to maintain, repair and restore joints and connective tissue.

Nodens Cat hip and Joint is a safe and all natural supplement that consists of powerful joint ingredients including glucosamine, chondroitin, hyaluronic acid and Opti-MSM to help reduce inflammation, stiffness, and pain associated with osteoarthritis and degenerative joint disease in senior cats. You get the most widely used joint ingredients available in one convenient bottle.

Opti-MSM is a premium, kosher, hypo-allergenic, distilled, purest, and safest MSM manufactured in the United States and is the only MSM supported by double-blind clinical research. Every batch of Opti-MSM is distilled four times and rigorously third-party tested to ensure purity. 

Nodens Cat Hip and Joint is a liquid formula that is convenient and easy to administer with your cat's daily meals. The liquid formula not only provides tasty beef flavor that your cat will absolutely love, the fast absorption also allows your cat to experience a fast result. In fact, customers are seeing happier and more energetic cats that can jump, play, and have fun pain free in as little as a few days. 

Don't let the 2 ounce bottle fool you. This bottle will last an average cat for 2 months. This product is made with 100% pure high quality human grade ingredients with the quality and safety you can trust. It contains no sugar, starch, salt, wheat, gluten, yeast, milk, or soy derivatives, which is great for cats with many allergies.

Nodens Cat Hip and Joint has over three hundred reviews and majority of cat owners have left positive feedback. If your cat is suffering from joint problems and have tried many things with no success, this may be the supplement your cat needs. Click below to see what other users are saying about this product:

Amazon's Customer Ratings: 4.5 Stars 


  • Manages hip and joint pain
  • Fast results
  • Contains Opti-MSM
  • 100% pure high quality human grade ingredients
  • No negative side effects
  • Made is USA
  • Safe and natural
  • 30 day money back guarantee
  • Free of shellfish allergens


  • Complains of bitter taste
  • Some cats don't respond to this product

3. Nature's Pure Edge MSM Supplement

Nature's Pure Edge MSM is another great MSM product for cats. It help with joint recover and alleviates allergy symptoms quickly. This MSM is a great choice for finicky cat eaters. Your cat will love the yummy chicken flavored MSM.

You would only need to administer MSM to your cat once per day. Each scoop contains 850 mg of easy-to-administer MSM powder. Simply sprinkle it directly on wet or dry food and you are done!

For picky eaters, I recommend that you mix with your pet's favorite moist food. This product can also be give to dogs. Make sure not to give this product to dogs or cats with urinary tract or bladder cancer, diabetes, or a recent operation.

This product will not only relieve your cat or dogs allergy symptoms and promotes joint flexibility, it also enhances joint circulation and promotes healthy hair, skin, and joint cartilage by boosting keratin production.

If that is not enough to like this product, you will also like the following:

  • Protects your cat's cartilage and skin from deterioration
  • Helps alleviate allergy symptoms including watery eyes, skin irritation, and sneezing
  • Improves your cat's skin and hair by stimulating keratin growth 
  • MSM increases glutathione levels, a natural antioxidant in the body

As you can see, there are many reasons to give Nature's Pure Edge MSM a try. If you would like to see what other users are saying about this supplement, click below to learn more:

Amazon's Customer Ratings: 4.0 Stars


  • MSM flavored with 100% real chicken
  • Made in USA
  • Enhance joint circulation 
  • Aids allergy symptoms 
  • Promotes healthy fur, skin, and joint cartilage 
  • Great for dogs and cats of all ages and sizes
  • No grain, soy, gluten, corn, or preservatives 
  • Great for picky eaters


  • Complain about safety seal 

4. Lexelium Joint Support

It’s very common for cats to have joint and bone problems as they age. Lexelium Joint Support is a vet recommended formula to help out your feline friends that are suffering from arthritis and joint issues by reducing inflammation, lubricating the joint, and promoting joint mobility. Additionally, this product may also help your cat reduce some symptoms from autoimmune diseases in the joints.

This product also contains glucosamine, chondroitin, and MSM to help protect your cat from further cartilage breakdown and reverse the effects of joint damage. All ingredients are sourced and manufactured in USA from local suppliers so you can rest assured with product quality and safety.

  • Glucosamine is used by the body to produce a variety of chemicals that are involved in building tendons, ligaments, cartilage, and the thick fluid that surrounds joints.
  • Chondroitin sulfate is used to stimulate the production of new cartilage while inhibiting the enzymes that break down cartilage.
  • MSM (Methylsulfonylmethane) is an organic compound that’s used to reduce inflammation and help regenerate healthy body tissue.  

This product also contains collagen hydrolysate, turmeric extract, burdock root, calendula extract, zinc gluconate, selenium, bay leaf extract, vitamin D3, and sprouted wheat for a more complete care for your furry friend.

This supplement is multi pet convenient. It is not only for cats, it is also effective as a dog joint supplement. This formula comes in powder form which can easily be mixed with wet and dry food.

You will also like that this supplement offers 30 day money back guarantee. If your cat is not getting the full benefit from this product or for whatever reason, contact the manufacturer within 30 days and they will give you a full refund.

As you can see there's a lot to love about Lexelium Joint Support. In fact, there're many positive reviews on Amazon and some have noticed improvement in about 2 to 3 weeks. If you want to see what other customers are saying about this product, click below:

Amazon's Customer Ratings: 4.5 Stars


  • Powerful cat and dog arthritis supplement
  • Veterinary formula for hip and joint health
  • Multi pet convenient
  • Contains many healthy ingredients
  • All ingredients sourced and manufactured in USA
  • 100% natural pet supplement 
  • 100% satisfaction guaranteed or you get your money back
  • Every Ingredient Is Backed by Veterinary Science


  • Some may not like the taste 

5. Kala Health MSm Powder

It's hard to see your cat starting to slow down as it grows older, but with a few teaspoons a day of Kala Health MSM, you can easily change all that. 

kala Health MSM is also made with Opti-MSM. As mentioned previously that Opti-MSM is the purest and only GRAS-designated MSM that is supported by double-blind clinical research. It is the only MSM on the market that undergoes a quadruple distillation and every batch is third-party tested, ensuring optimal purity, quality, and consistency.

This supplement contains no harmful chemicals so you can rest assured that you're getting a product with premium natural ingredients that your cat will love taking and benefiting from. This product has exceptionally low toxicity and your cat can take it daily over a long period of time to help maintain good joint health. 

The powder has a very long shelf life that will not clump, which is a common problem with other MSM brands. The powder dissolves very well and this makes it easy to administer to your cat. This product is available in 1, 10, or 33 pounds. The 33 pounds is a smart purchase that is great value for money. 

The reviews on Amazon are almost all positive. If you want to see what other feline parents are saying about  Kala Health MSM, click the red button below to learn more:

Amazon's Customer Ratings: 4.8 Stars 


  • Contains 99.9 % pure MSM powder
  • Made in the United States 
  • Great for cats and dogs 
  • Promotes a shiny coat and healthy skin
  • Helps increase energy
  • Supports healthy joints
  • Free of additives 
  • Reasonably priced  


  • Some pets don't like the taste


Getting your cat a MSM supplement is a sure-fire way to help with their joint and pain issues, and promote optimal overall health, wellness, coat appearance, and much more.

There are some fantastic products out there that are designed to keep your pet well. Make sure you think about what you want your cat supplements to have by checking out our buying guide above before you make your final purchase. Enjoy!

6 Comments on “Best MSM For Cats: Buying Guide & Our Top Picks (Review 2020)”

  1. Lovely article. I had no idea what MSM was until I read your article. The last cat I had was about 40 years ago. He was a tough cat. We lived in open fields so I thought of not fixing him so that he could defend himself. He did get in a lot of fights. He would come home with wounds of large bites. He was a big cat too. He came home every night for 7 years but on the night he didn’t return I knew that something got him. We lived in an area that had lots of coyotes. Thanks for writing this article. It brought memofries from the life of my cat.

    1. Hello Courtney,

      Thank you for sharing your story. Your story reminded me of my cat that also didn’t return and I am not sure what exactly happened to her. I still miss her to this day.


  2. Good evening! Excellent article. I love cats, and I had no idea that sulfur affected them as extensively as it does. I greatly appreciate how you broke your picks down and explained everything in a thorough, objective fashion. Although I don’t have any cats (I have two dogs), if I ever decide to get a cat, I will definitely refer to your site for cat food options. I have saved your site and will definitely share it with my friends and family. God bless you!

    1. Hello C.N.,

      I appreciate your comment and you haring my website with others. A lot of these MSM supplements for cats can also be given to dogs for joint issues. I have another post where I share my top picks of MSM for dogs. Feel free to check it out.

      Best regards,

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